16. 06. 2025, 13:00

Mucinomika kot naslednji mejnik masne sprektrometrije

Video
16. 06. 2025, 13:00

Mucinomika kot naslednji mejnik masne sprektrometrije

Video
doc. dr. Stacy Malaker
Univerza Yale, ZDA
Stacy Malaker je docentka na Oddelku za kemijo Univerze Yale. Je prejemnica več nagrad, med drugim nagrade Chemistry Biology Interface Division Horizon Prize Kraljeve družbe za kemijo.
Glikoproteini z mucinsko domeno so močno O-glikozilirani in igrajo ključno vlogo pri številnih bioloških funkcijah. Vendar pa njihova močna O-glikozilacija ni povsem pojasnjena, tako z vidika glikoproteomike kot z vidika strukturne dinamike, predvsem zaradi izzivov, povezanih s proučevanjem mucinskih domen. V predavanju bom predstavila napredek v masni spektrometrični analizi mucinov, vključno s karakterizacijo mucinaz, tehnikami obogatitve in popolnim mucinomskim kartiranjem translacijsko pomembnih mucinskih proteinov.
doc. dr. Stacy Malaker
Univerza Yale, ZDA
Stacy Malaker je docentka na Oddelku za kemijo Univerze Yale. Je prejemnica več nagrad, med drugim nagrade Chemistry Biology Interface Division Horizon Prize Kraljeve družbe za kemijo.

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Prof. Dr. Atish Dabholkar, International Centre for Theoretical Physics (ICTP), Trieste, Italy

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Prof. Dr. Alojz Kodre, Faculty of Mathematics and Physics, University of Ljubljana

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